The heritability of metabolite concentrations in stored human red blood cells
نویسندگان
چکیده
منابع مشابه
Alterations in cell surface area and deformability of individual human red blood cells in stored blood
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusion. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various periods with and without a preservation solution called CPDA-1. With 3-D quantitative phase imaging techniques, the op...
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We have developed a method for measuring the red blood cell (RBC) membrane overall elasticity μ by measuring the deformation of the cells when dragged at a constant velocity through a plasma fluid by an optical tweezers. The deformability of erythrocytes is a critical determinant of blood flow in the microcirculation. We tested our method and hydrodynamic models, which included the presence of ...
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Hemolysis has been reported in red blood cells (RBCs) that have undergone leukocyte-reduction filtration. This study investigated whether the age of RBCs or the filter type affected hemolysis. One hundred eighty units of RBCs (adenine-saline added) were leukocyte-reduced by filtration. At each of the 6 weeks of shelf life, 10 units were filtered with the "BPF4" filter, 10 units with the "Purece...
متن کاملEffects of High Doses of X-Ray on Hematological Parameters and Morphology of Red Blood Cells in Human Blood
Introduction: The aim of the current study was to investigate the effects of X-ray radiation on some hematological parameters, morphology of red blood cells (RBC) and erythrocyte sedimentation rate (ESR) analysis of human blood using computed tomography (CT) scanner. Material and Methods: For the purpose of the study, 5 ml of wholeblood was drawn from vein puncture of 28 healthy people and div...
متن کاملA Root Cause Analysis of Haemolysis Encountered in Leuco-filtration of Stored Packed Red Cells Units
Background and Aims: Leukoreduction of blood components has reduced the incidence of transfusion-associated adverse events. Leucofiltration is the most effective method of leukoreduction. We encountered haemolysis in a series of leucofiltered units. This stressed our precious inventory, added to financial loss, increased our turn-around time to issue leucofiltered blood units, and placed doubts...
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ژورنال
عنوان ژورنال: Transfusion
سال: 2014
ISSN: 0041-1132
DOI: 10.1111/trf.12605